The Nirvanol Treatment of Chorea.
نویسنده
چکیده
Since the introduction of nirvanol in the treatment of chorea by Roeder' in 1919, it has been used by many workers, particularly in Germany, and it was introduced into this country in 1929 by Poynton and Schlesinger2. Details of its composition and general use may be found in many papers, notably those of Lesigang3 in German and Poynton and Schlesinger in English, and it is the intention in the present paper to discuss those points in which there may be difference from papers already published, thus to some extent avoiding unnecessary recapitulation. During 1929 a number of cases were treated at the East London Hospital for Children, and of these eleven have been already published by Whitaker4, but, by arrangement with him, they have been included in the present series, as the present writer was able to follow them from the beginning and to see them as out-patients later, thus being able to present a more complete picture.
منابع مشابه
Sydenham's Chorea
Sydenham’s chorea is a delayed complication of group Aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.It is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. It is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with Sydenham’schorea produce antibodies that cross reac...
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Anticonvulsants have long been recognized as a cause of hypersensitivity reactions. Phenytoin hypersensitivity can be traced to 1916, when phenylethylhydantoin (phenytoin sodium), which was used to treat children with Sydenham chorea, was found to induce a hypersensitivity reaction. Phenytoin was then known as a “nerve sedative,” and the hypersensitivity reaction, “nirvanol sickness,” resolved ...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 5 30 شماره
صفحات -
تاریخ انتشار 2007